Human VCAM-1 ELISA Kit PicoKine®

SKU: EK0537

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: VCAM1

Specificity: Natural and recombinant human VCAM-1

Background: Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface glycoprotein adhesive for certain blood leukocytes and tumor cells, which is expressed by activated endothelium in a variety of pathologic conditions including atherosclerosis. Increased expression of VCAM1 is associated with a variety of chronic inflammatory conditions, making its expression and function a target for therapeutic intervention. Integrin alpha4beta1 (VLA-4) and VCAM-1 facilitate a critical cell-cell adhesion event required for survival of endothelial and mural cells during vascularization. The VCAM1 gene is assigned to the 1p31-32 region of chromosome 1 based on the analysis of human-mouse hybrid cell lines and in situ hybridization. The standard product used in this kit is recombinant human VCAM-1, consisting of Phe25-Glu698 amino acid sequence of a single chain with the molecular mass of 74KDa. As a result of glycosylation, the molecular mass of 90-95KDa is revealed by SDS-PAGE.

Immunogen: Expression system for standard: NS0; Immunogen sequence: F25-E698

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Reference:

Uniprot ID: P19320

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 7412

Protein Name: Vascular cell adhesion protein 1

Gene Full Name: vascular cell adhesion molecule 1

Synonyms: CD106; INCAM 100; V CAM 1; VCAM 1; VCAM1