Human ULBP1 ELISA Kit PicoKine®

SKU: EK1685

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: ULBP1

Specificity: Natural and recombinant human ULBP1

Background: UL16 binding protein 1 (ULBP1) is a cell surface glycoprotein encoded by ULBP1 gene located on the chromosome 6. ULBP1 is related to MHC class I molecules, but its gene maps outside the MHC locus. The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: G26-G216

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Reconstitution:

Reference:

Uniprot ID: Q9BZM6

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Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 80329

Protein Name: UL16-binding protein 1

Gene Full Name: UL16 binding protein 1

Synonyms: ALCAN beta; N2DL 1; N2DL1; NKG2D ligand 1; NKG2DL1; RAET1I; UL16 binding protein 1; ULBP1