Human Transient Receptor Potential Cation Channel Subfamily V Member 6, TRPV6 ELISA Kit

SKU: E6307Hu

Size:96 Tests-1 Kit

Background:Calcium selective cation Channel that mediates Ca(2+) uptake in various tissues, including the intestine (PubMed: 11097838, PubMed: 11278579, PubMed: 11248124 PubMed: 15184369, PubMed: 23612980, PubMed: 29258289). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin (By similarity). The Channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification (PubMed: 15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify Channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.

Research_area:Others

Applications:ELISA

Target_protein:TRPV6

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.26ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Transient Receptor Potential Cation Channel Subfamily V Member 6

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9H1D0

MASS(Da):87,286

GeneID:55503

Synonyms:Calcium transport protein 1;CaT1;CaT-L;CaT-like;ECaC2;Epithelial calcium Channel 2;Transient receptor potential cation Channel subfamily V member 6;TRPV 6;TRPV6;

Gene names:TRPV6

Standard solution:3200ng/L