Human Total FGFR3 ELISA Kit PicoKine®

SKU: EK2382

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: FGFR3

Specificity: Natural and recombinant human total FGFR3

Background: Fibroblast growth factor receptor 3, also known as CD333, is a protein that in humans is encoded by the FGFR3 gene. This gene encodes a member of the fibroblast growth factor receptor(FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. The FGFR3 gene is mapped to the HD region on chromosome 4p16.3. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia.

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Uniprot ID: P22607

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 2261

Protein Name:

Gene Full Name: Fibroblast growth factor receptor 3

Synonyms: Fibroblast growth factor receptor 3; FGFR-3; 2.7.10.1; CD333; FGFR3; JTK4