Human TNFRSF25/DR3 ELISA Kit PicoKine®

SKU: EK1579

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: TNFRSF25

Specificity: Natural and recombinant human TNFRSF25

Background: Death receptor 3 (DR3), also known as tumor necrosis factor receptor superfamily member 25 (TNFRSF25), is a cell surface receptor of the tumor necrosis factor receptor superfamily which mediates apoptotic signalling and differentiation. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q25-F201

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Uniprot ID: Q93038

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 8718

Protein Name: Tumor necrosis factor receptor superfamily member 25

Gene Full Name: TNF receptor superfamily member 25

Synonyms: APO 3; APO3; DDR3; Death receptor 3; DR3; LARD; Protein WSL; Protein WSL 1; TNFRSF12; TNFRSF25; TR3; TRAMP; WSL; WSL 1; WSL LR; WSL1