Human Tnfaip3-interacting Protein 3, TNIP3 ELISA Kit

SKU: E6280Hu

Size:96 Tests-1 Kit

Background:Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

Research_area:Signal Transduction; Cardiovascular

Applications:ELISA

Target_protein:TNIP3

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.06ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:TNFAIP3-interacting protein 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q96KP6

MASS(Da):38,943

GeneID:79931

Synonyms:A20-binding inhibitor of NF-kappa-B activation 3;ABIN-3;LIND;Listeria-induced gene protein;TNFAIP3-interacting protein 3;TNIP3

Gene names:TNIP3

Standard solution:3200ng/L