Human TNF-related apoptosis-inducing ligand receptor 1,TRAIL-R1 ELISA KIT

SKU: E1830Hu

Size:96 Tests-1 Kit

Background:Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (PubMed:19090789). Promotes the activation of NF-kappa-B (PubMed:9430227). {ECO:0000269|PubMed:19090789, ECO:0000269|PubMed:9430227}.

Research_area:

Applications:ELISA

Target_protein:TNFRSF10A

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.21ng/ml

Detection range:0.38-24ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:tumor necrosis factor-related apoptosis-inducing ligand receptor 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O00220

MASS(Da):50089

GeneID:8797

Synonyms:TNFRSF10A APO2 DR4 TRAILR1

Gene names:TNFRSF10A

Standard solution:48ng/ml