GeneBio Systems
Human Stanniocalcin 1 / STC1 / STC ELISA Kit PicoKine®
Human Stanniocalcin 1 / STC1 / STC ELISA Kit PicoKine®
SKU:EK1404
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Size: 96 wells/kit, with removable strips.
Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Form:
Reactivity: Human
Applications: ELISA
Application Details:
Gene Name: STC1
Specificity: Natural and recombinant human STC1
Background: Stanniocalcin-1 is a glycoprotein which is encoded by the STC1 gene. This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. Human Stanniocalcin-1 is a putative molecular biomarker of leukemic microenvironment and the only molecular function known up to date is a SUMO E3 ligase activity in the SUMOylation cycle. STC1 interacts with lots of proteins in the cytoplasm, mitochondria, endoplasmatic reticulum and dot-like fashion in the nucleus. The N-terminal region of STC1 is the function region which is responsible to establish the interaction with its partners, including SUMO1. Low resolution studies shows that STC1 is an anti-parallel homodimer in solution and the cystein 202 is responsible for the dimerization of this protein. All the 5 dissulfide bonds of human STC1 are conserved and have the same profile of fish STC.
Immunogen: Expression system for standard: NS0; Immunogen sequence: V34-A247
Clonality:
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Reconstitution:
Reference:
Uniprot ID: P52823
Host:
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Conjugate:
Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
Isotype:
Phospho_site:
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Gene ID: 6781
Protein Name: Stanniocalcin-1
Gene Full Name: stanniocalcin 1
Synonyms: stanniocalcin 1; STC; STC 1; STC1
