Human Sodium Channel Protein Type 9 Subunit Alpha, SCN9A ELISA Kit

SKU: E6730Hu

Size:96 Tests-1 Kit

Background:Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective Channel through which Na(+) ions may pass in accordance with their electrochemical gradient (PubMed: 7720699, PubMed: 17167479, PubMed: 25240195, PubMed: 26680203, PubMed: 15385606, PubMed: 16988069, PubMed: 17145499, PubMed: 19369487, PubMed: 24311784). It is a tetrodotoxin-sensitive Na(+) Channel isoform (PubMed: 7720699). Plays a role in pain mechanisms, especially in the development of inflammatory pain (PubMed: 17167479, PubMed: 17145499, PubMed: 19369487, PubMed: 24311784).

Research_area:Neuroscience

Applications:ELISA

Target_protein:SCN9A

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.19ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Sodium Channel Protein Type 9 Subunit Alpha

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q15858

MASS(Da):226,372

GeneID:6335

Synonyms:hNE-Na;Neuroendocrine sodium Channel;Peripheral sodium Channel 1;PN1;SCN9A;Sodium Channel protein type 9 subunit alpha;Sodium Channel protein type IX subunit alpha;Voltage-gated sodium Channel subunit alpha Nav1.7

Gene names:SCN9A

Standard solution:3200ng/L