Human Reelin, RELN ELISA Kit

SKU: E6072Hu

Size:96 Tests-1 Kit

Background:Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity).

Research_area:Neuroscience

Applications:ELISA

Target_protein:RELN

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.027ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Reelin

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P78509

MASS(Da):388,388

GeneID:5649

Synonyms:Reelin;RELN

Gene names:RELN

Standard solution:24ng/mL