Human Protein Tyrosine Phosphatase Non Receptor Type 14,PTPN14 ELISA KIT

SKU: E3812Hu

Size:96 Tests-1 Kit

Background:Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell-matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial-mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor. {ECO:0000269|PubMed:10934049, ECO:0000269|PubMed:12808048, ECO:0000269|PubMed:17893246, ECO:0000269|PubMed:20826270, ECO:0000269|PubMed:22233626, ECO:0000269|PubMed:22525271, ECO:0000269|PubMed:22948661}.

Research_area:

Applications:ELISA

Target_protein:PTPN14

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.051ng/ml

Detection range:0.1-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Protein Tyrosine Phosphatase Non Receptor Type 14

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q15678

MASS(Da):135261

GeneID:5784

Synonyms:PTPN14 PEZ PTPD2

Gene names:PTPN14

Standard solution:32ng/ml