Human Protein (Peptidylprolyl Cis, Trans Isomerase) Nima-interacting 1, PIN1 ELISA Kit

SKU: E0656Hu

Size:96 Tests-1 Kit

Background:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 is an enzyme that in humans is encoded by the PIN1 gene. Pin 1, or peptidyl-prolyl cis/trans isomerase (PPIase), isomerizes only phospho-Serine/Threonine-Proline motifs. The enzyme binds to a subset of proteins and thus plays a role as a post phosphorylation control in regulating protein function. Studies have shown that the deregulation of Pin1 may play a pivotal role in various diseases. Notably, the up-regulation of Pin1 is implicated in certain cancers, and the down-regulation of Pin1 is implicated in Alzheimer's disease. Inhibitors of Pin1 may have therapeutic implications for cancer and immune disorders.

Research_area:Neuroscience; Cell Biology

Applications:ELISA

Target_protein:PIN1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.29ng/L

Detection range:0.5-200ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:protein(peptidylprolyl cis/trans isomerase) NIMA-interacting 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q13526

MASS(Da):18,243

GeneID:5300

Synonyms:DOD;Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1;Peptidyl-prolyl cis-trans isomerase Pin1;PIN1;PPIase Pin1;Rotamase Pin1;UBL5

Gene names:PIN1

Standard solution:240ng/L