Human Prostaglandin I Synthase,PTGIS ELISA KIT

SKU: E4542Hu

Size:96 Tests-1 Kit

Background:Catalyzes the biosynthesis and metabolism of eicosanoids. Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2), a potent mediator of vasodilation and inhibitor of platelet aggregation (PubMed:18032380, PubMed:25623425, PubMed:12372404, PubMed:15115769). Additionally, displays dehydratase activity, toward hydroperoxyeicosatetraenoates (HPETEs), especially toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) (PubMed:17459323). {ECO:0000269|PubMed:12372404, ECO:0000269|PubMed:15115769, ECO:0000269|PubMed:17459323, ECO:0000269|PubMed:18032380, ECO:0000269|PubMed:25623425}.

Research_area:

Applications:ELISA

Target_protein:PTGIS

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.119ng/mL

Detection range:0.2-70ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Prostaglandin I Synthase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q16647

MASS(Da):57104

GeneID:5740

Synonyms:PTGIS CYP8 CYP8A1

Gene names:PTGIS

Standard solution:80ng/mL