Human Properdin/Complement Factor P EZ-Set™ ELISA Kit (DIY Antibody Pairs)

SKU: EZ1653

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CFP

Specificity: Natural and recombinant human Properdin

Background: Properdin or Factor P is the only known positive regulator of complement activation that stabilizes thealternative pathway convertases. This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Immunogen: Expression system for standard: NS0; Immunogen sequence: D28-L469

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Reconstitution:

Reference:

Uniprot ID: P27918

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

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Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 5199

Protein Name: Properdin

Gene Full Name: complement factor properdin

Synonyms: BFD; CFP; Complement factor P; complement factor properdin; PFC; PFD; PROPERDIN