Human Platelet-derived Growth Factor C, PDGF-C ELISA Kit

SKU: E3073Hu

Size:96 Tests-1 Kit

Background:Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function.

Research_area:Cardiovascular

Applications:ELISA

Target_protein:PDGFC

Reactivity:Human

Assay type:Sandwich

Sensitivity:3.12ng/L

Detection range:5-1000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Platelet-Derived Growth Factor C

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9NRA1

MASS(Da):39,029

GeneID:56034

Synonyms:Fallotein;PDGF C;PDGFC;PDGF-C;PDGFC latent form;PDGFC receptor-binding form;Platelet-derived growth factor C;Platelet-derived growth factor C, latent form;Platelet-derived growth factor C, receptor-binding form;SCDGF;Spinal cord-derived growth factor;VEGF-E

Gene names:PDGFC

Standard solution:1280ng/L