Human PERQ amino acid-rich with GYF domain-containing protein 2,GIGYF2 ELISA KIT

SKU: E2077Hu

Size:96 Tests-1 Kit

Background:Key component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation (PubMed:22751931, PubMed:31439631). In the 4EHP-GYF2 complex, acts as a factor that bridges EIF4E2 to ZFP36/TTP, linking translation repression with mRNA decay (PubMed:31439631). Also recruits and bridges the association of the 4EHP complex with the decapping effector protein DDX6, which is required for the ZFP36/TTP-mediated down-regulation of AU-rich mRNA (PubMed:31439631). May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling, including IGF1 and insulin receptors (PubMed:12771153). {ECO:0000269|PubMed:12771153, ECO:0000269|PubMed:22751931, ECO:0000269|PubMed:31439631}.

Research_area:

Applications:ELISA

Target_protein:GIGYF2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.24ng/ml

Detection range:0.5-32ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:PERQ amino acid-rich with GYF domain-containing protein 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q6Y7W6

MASS(Da):150070

GeneID:26058

Synonyms:GIGYF2 KIAA0642 PERQ2 TNRC15

Gene names:GIGYF2

Standard solution:64ng/ml