Human Nuclear Receptor Coactivator 3, NCOA3 ELISA Kit

SKU: E5795Hu

Size:96 Tests-1 Kit

Background:Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit.

Research_area:Epigenetics and Nuclear Signaling; Signal Transduction; Cancer; Metabolism

Applications:ELISA

Target_protein:NCOA3

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.48ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Nuclear receptor coactivator 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9Y6Q9

MASS(Da):155,293

GeneID:8202

Synonyms:ACTR;AIB1;AIB-1;Amplified in breast cancer 1 protein;bHLHe42;CAGH16;CBP-interacting protein;Class E basic helix-loop-helix protein 42;KAT13B;NCOA3;NCoA-3;Nuclear receptor coactivator 3;pCIP;RAC3;RAC-3;Receptor-associated coactivator 3;SRC3;SRC-3;Steroid receptor coactivator protein 3;Thyroid hormone receptor activator molecule 1;TNRC14;TNRC16;TRAM-1

Gene names:NCOA3

Standard solution:2400ng/L