Human Nf-Kappa-B Inhibitor Alpha, NFKBIA ELISA Kit

SKU: E5772Hu

Size:96 Tests-1 Kit

Background:Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:NFKBIA

Reactivity:Human

Assay type:Sandwich

Sensitivity:14.01ng/L

Detection range:30-9000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Nf-Kappa-B Inhibitor Alpha

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P25963

MASS(Da):35,609

GeneID:4792

Synonyms:IkappaBalpha;I-kappa-B-alpha;IkB-alpha;Major histocompatibility complex enhancer-binding protein MAD3;NF-kappa-B inhibitor alpha;NFKBIA

Gene names:NFKBIA

Standard solution:9600ng/L