Human Neurogenic Locus Notch Homolog Protein 4, NOTCH4 ELISA Kit

SKU: E3264Hu

Size:96 Tests-1 Kit

Background:Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:NOTCH4

Reactivity:Human

Assay type:Sandwich

Sensitivity:14.71ng/L

Detection range:30-9000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Neurogenic locus notch homolog protein 4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q99466

MASS(Da):209,622

GeneID:4855

Synonyms:hNotch4;INT3;Neurogenic locus notch homolog protein 4;Notch 4;Notch 4 extracellular truncation;Notch 4 intracellular domain];NOTCH4

Gene names:NOTCH4

Standard solution:9600ng/L