Human Netrin-1, NTN1 ELISA Kit

SKU: E1277Hu

Size:96 Tests-1 Kit

Background:Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (PubMed: 28483977). Involved in dorsal root ganglion axon projection towards the spinal cord (PubMed: 28483977). It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis (PubMed: 15343335).

Research_area:Neuroscience

Applications:ELISA

Target_protein:NTN1

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.39pg/ml

Detection range:10-3000pg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Netrin-1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O95631

MASS(Da):67,748

GeneID:9423

Synonyms:Epididymis tissue protein Li 131P;Netrin-1;NTN 1;NTN1

Gene names:NTN1

Standard solution:4800pg/ml