Human Nadh-ubiquinone Oxidoreductase 75 kDa Subunit, NDUFS1 ELISA Kit

SKU: E6754Hu

Size:96 Tests-1 Kit

Background:NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (NDUFS1) is an enzyme that in humans is encoded by the NDUFS1 gene. The encoded protein, NDUFS1, is the largest subunit of complex I, located on the inner mitochondrial membrane, and is important for mitochondrial oxidative phosphorylation. Mutations in this gene are associated with complex I deficiency. The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized.

Research_area:Tags & Cell Markers; Neuroscience; Cancer; Metabolism

Applications:ELISA

Target_protein:NDUFS1

Reactivity:Human

Assay type:Sandwich

Sensitivity:11.11ng/L

Detection range:20-3800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:NADH-ubiquinone oxidoreductase 75 kDa subunit

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P28331

MASS(Da):79,468

GeneID:4719

Synonyms:CI-75k;CI-75Kd;Complex I-75kD;MC1DN5;NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial;NDUFS1;PRO1304

Gene names:NDUFS1

Standard solution:4000ng/L