Human Nacht, Lrr and Pyd Domains-containing Pprotein 2, NLRP2 ELISA Kit

SKU: E4050hu

Size:96 Tests-1 Kit

Background:Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.

Research_area:Cell Biology

Applications:ELISA

Target_protein:NLRP2

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.12ng/L

Detection range:10-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:NACHT,LRR and PYD domains-containing protein 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9NX02

MASS(Da):120,515

GeneID:55655

Synonyms:CLR19.9;NACHT, LRR and PYD domains-containing protein 2;NALP2;NBS1;NLRP2;Nucleotide-binding site protein 1;PAN1;PYPAF2;PYRIN domain and NACHT domain-containing protein 1;PYRIN-containing APAF1-like protein 2

Gene names:NLRP2

Standard solution:3200ng/L