Human Mitochondrial Import Inner Membrane Translocase Subunit Tim8 A, TIMM8A ELISA Kit

SKU: E4311hu

Size:96 Tests-1 Kit

Background:Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:TIMM8A

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.56ng/L

Detection range:20-3500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Mitochondrial import inner membrane translocase subunit Tim8 A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O60220

MASS(Da):10,998

GeneID:1678

Synonyms:DDP;DDP1;Deafness dystonia protein 1;DFN1;Mitochondrial import inner membrane translocase subunit Tim8 A;MTS;TIM8;TIMM8A;X-linked deafness dystonia protein;

Gene names:TIMM8A

Standard solution:4000ng/L