Human Metalloprotease TIKI1,TRABD2A ELISA KIT

SKU: E7659Hu

Size:96 Tests-1 Kit

Background:Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation. {ECO:0000269|PubMed:22726442}.

Research_area:

Applications:ELISA

Target_protein:TRABD2A

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.12ng/ml

Detection range:0.25-16ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q86V40

MASS(Da):57676

GeneID:129293

Synonyms:TRABD2A C2orf89 TIKI1

Gene names:TRABD2A

Standard solution:32ng/ml