Human Menin, MEN1 ELISA Kit

SKU: E5662Hu

Size:96 Tests-1 Kit

Background:Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.

Research_area:Others

Applications:ELISA

Target_protein:MEN1

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.03ng/L

Detection range:20-3500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Menin

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O00255

MASS(Da):68,023

GeneID:4221

Synonyms:MEN 1;MEN1;Menin

Gene names:MEN1

Standard solution:4000ng/L