Human Low Affinity Immunoglobulin Gamma Fc Region Receptor 2B, FCGR2B ELISA Kit

SKU: E3905Hu

Size:96 Tests-1 Kit

Background:Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.

Research_area:Immunology

Applications:ELISA

Target_protein:FCGR2B

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.13ng/ml

Detection range:0.3-90ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Low affinity immunoglobulin gamma Fc region receptor 2-b

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P31994

MASS(Da):34,044

GeneID:2213

Synonyms:CD antigen CD32;CD32;CD32B;CDw32;FCG2;Fc-gamma RII-b;Fc-gamma-RIIb;FCGR2;FCGR2B;FCGR2C;FcRII-b;IGFR2;IgG Fc receptor II-b;Low affinity immunoglobulin gamma Fc region receptor II-b

Gene names:FCGR2B

Standard solution:96ng/ml