Human LILRB1 EZ-Set™ ELISA Kit (DIY Antibody Pairs)

SKU: EZ2123

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: LILRB1

Specificity: Natural and recombinant human LILRB1

Background: Leukocyte immunoglobulin-like receptors (LILRs), also called CD85s, ILTs, or LIRs, are important mediators of immune activation and tolerance that contain tandem immunoglobulin (Ig)-like folds. LILRB1 is encoded within the leukocyte receptor complex on 19q13.4, previously implicated to be a susceptibility region to systemic lupus erythematosus (SLE).LILRB1 binds to a wide range of major histocompatibility complex class I molecules (MHCIs) and transduces negative signals that can, for example, prevent killing of MHCI-expressing cells.LILRB1 transcription is correlated with surface protein expression on NK cells.

Immunogen: Expression system for standard: NS0; Immunogen sequence: G24-V461

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Reference:

Uniprot ID: Q8NHL6

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 10859

Protein Name: Leukocyte immunoglobulin-like receptor subfamily B member 1

Gene Full Name: leukocyte immunoglobulin like receptor B1

Synonyms: CD85; CD85J; ILT 2; ILT2; LILRB1; LIR 1; LIR1; MIR 7; MIR7