Human Leucine-rich Glioma-inactivated Protein 1, LGI1 ELISA Kit

SKU: E5562Hu

Size:96 Tests-1 Kit

Background:Regulates voltage-gated potassium Channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down Channel inactivation by precluding Channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.

Research_area:Neuroscience

Applications:ELISA

Target_protein:LGI1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.021ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Leucine-Rich Glioma-Inactivated Protein 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O95970

MASS(Da):63,818

GeneID:9211

Synonyms:Epitempin-1;Leucine-rich glioma-inactivated protein 1;LGI 1;LGI1

Gene names:LGI1

Standard solution:24ng/mL