Human Lactosylceramide 4-alpha-galactosyltransferase, A4GALT ELISA Kit

SKU: E5550Hu

Size:96 Tests-1 Kit

Background:Catalyzes the transfer of galactose from UDP-alpha-D-galactose to lactosylceramide/beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide(d18:1(4E)) to produce globotriaosylceramide/globoside Gb3Cer (d18:1(4E)) (PubMed:10748143). Also able to transfer galactose to galactosylceramide/beta-D-Gal-(1<->1')-Cer (PubMed:10748143). Globoside Gb3Cer is a glycosphingolipid of the globo serie, one of the major types of neutral root structures of glycosphingolipids, that constitute a significant portion of mammalian cell membranes (Probable). Globotriaosylceramide/globoside Gb3Cer in blood and tissue cell membranes is the antigen Pk of blood histogroup P (PubMed:10747952). (Microbial infection) Globotriaosylceramide is one of the cellular ligands for bacterial verotoxins.

Research_area:Cardiovascular

Applications:ELISA

Target_protein:A4GALT

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.66ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Lactosylceramide 4-alpha-galactosyltransferase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9NPC4

MASS(Da):40,499

GeneID:53947

Synonyms:A14GALT;A4GALT;Alpha-1,4-galactosyltransferase;Alpha-1,4-N-acetylglucosaminyltransferase;Alpha4Gal-T1;CD77 Synthase;Gb3 Synthase;Gb3S;Globotriaosylceramide Synthase;Lactosylceramide 4-alpha-galactosyltransferase;P(k);P1;P1/Pk Synthase;P1PK;PK;UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase

Gene names:A4GALT

Standard solution:3200ng/L