Human Junctional Adhesion Molecule A, F11R ELISA Kit

SKU: E2768Hu

Size:96 Tests-1 Kit

Background:Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed: 11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed: 11812992). Involved in platelet activation (PubMed: 10753840). (Microbial infection) Acts as a receptor for Mammalian reovirus sigma-1. (Microbial infection) Acts as a receptor for Human Rotavirus strain Wa.

Research_area:Cardiovascular

Applications:ELISA

Target_protein:F11R

Reactivity:Human

Assay type:Sandwich

Sensitivity:10.11ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Junctional Adhesion Molecule A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9Y624

MASS(Da):32,583

GeneID:50848

Synonyms:CD antigen CD321;F 11R;F11R;JAM-1;JAM-A;Junctional adhesion molecule 1;Junctional adhesion molecule A;PAM-1;Platelet adhesion molecule 1;Platelet F11 receptor

Gene names:F11R

Standard solution:4800ng/L