Human Inward Rectifier Potassium Channel 16, KCNJ16 ELISA Kit

SKU: E1814Hu

Size:96 Tests-1 Kit

Background:Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance. In the kidney, together with KCNJ10, mediates basolateral K+ recycling in distal tubules; this process is critical for Na+ reabsorption at the tubules (PubMed:24561201).

Research_area:Neuroscience

Applications:ELISA

Target_protein:KCNJ16

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.05ng/ml

Detection range:0.1-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Inward rectifier potassium Channel 16

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9NPI9

MASS(Da):47,949

GeneID:3773

Synonyms:BIR9;HKTD;Inward rectifier K(+ Channel Kir5.1;Inward rectifier potassium Channel 16;KCNJ16;KIR5.1;Potassium Channel, inwardly rectifying subfamily J member 16

Gene names:KCNJ16

Standard solution:32ng/ml