Human IL-34/Interleukin-34 PicoKine® Quick ELISA Kit

SKU: FEK1365

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IL34

Specificity: Natural and recombinant Human IL34

Background: Interleukin-34, or IL-34 is a protein belonging to a group of cytokines called interleukins. It is mapped to 16q22.1. The discovery of IL-34 protein in the red pulp of the spleen suggests involvement in growth and development of myeloid cells, consistent with its activity on monocytes. IL-34 is a recently discovered cytokine that acts on tissue resident macrophages and Langerhans cells upon binding the receptor for CSF-1, CSF-1R. It also can promote the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor. In addition, it promotes the development, survival, and function of microglia and Langerhans cells, therefore, this cytokine may predominately function in brain and skin biology.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: N21-P242

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Uniprot ID: Q6ZMJ4

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 146433

Protein Name: Interleukin-34

Gene Full Name: interleukin 34

Synonyms: C16orf77; IL 34; IL34; IL-34; interleukin 34