Human IL-17RA ELISA Kit PicoKine®

SKU: EK0784

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IL17RA

Specificity: Natural and recombinant human IL-17RA

Background: Interleukin 17 receptor A, also known as IL17RA and CDw217 (cluster of differentiation w217), is a human gene. The IL17R gene is mapped to 22q11.22-q11.23 by radiation hybrid analysis. Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Also, it is showed that mouse Il17r bound HSV-13 and mouse Il17. Recombinant soluble Il17r inhibited mitogen-induced T-cell proliferation and Il2 production.

Immunogen: Expression system for standard: NS0; Immunogen sequence: L33-W320

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Reference:

Uniprot ID: Q96F46

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 23765

Protein Name: Interleukin-17 receptor A

Gene Full Name: interleukin 17 receptor A

Synonyms: interleukin 17 receptor A; CANDF5; CD217; CDw217; IL-17RA; IL17R; IMD51; hIL-17R; IL17RA; IL 17RA