Human IL-17/IL-17A ELISA Kit PicoKine®

SKU: EK0430

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IL17A

Specificity: Natural and recombinant human IL-17/IL-17A

Background: IL-17 is an inflammatory cytokine produced primarily by a unique lineage of CD4 T cells that plays critical roles in the pathogenesis of multiple autoimmune diseases. Interleukin-17 is expressed by activated T cells and is 57% identical to the 17- to 26-kD secretory glycoprotein encoded by gene 13 of the herpesvirus saimiri (HVS-13). IL17 induces nuclear factor kappa-B and the expression of IL6, intercellular adhesion molecule-1, granulocyte macrophage colony-stimulating factor,and prostaglandin E2, as well as the maturation of CD34 positive hematopoietic precursors into neutrophils. Anti-IL17 antibodies significantly inhibited osteoclast formation induced by culture media of RA synovial tissues. The standard product used in this kit is recombinant human IL-17, consisting of 136 amino acids with the molecular mass of 16KDa.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: I20-A155

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Reference:

Uniprot ID: Q16552

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 3605

Protein Name: Interleukin-17A

Gene Full Name: interleukin 17A

Synonyms: CTLA 8; CTLA8; IL 17; IL 17A; IL17; IL-17; IL17A; interleukin 17A