Human Hyaluronidase-3, HYAL3 ELISA Kit

SKU: E5441Hu

Size:96 Tests-1 Kit

Background:Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Has no hyaluronidase activity in embryonic fibroblasts in vitro. Has no hyaluronidase activity in granulosa cells in vitro.

Research_area:Others

Applications:ELISA

Target_protein:HYAL3

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.15ng/mL

Detection range:0.3-90ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Hyaluronidase-3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O43820

MASS(Da):46,501

GeneID:8372

Synonyms:HYAL 3;HYAL3;Hyal-3;Hyaluronidase-3;Hyaluronoglucosaminidase-3;LuCa-3;Lung carcinoma protein 3

Gene names:HYAL3

Standard solution:96ng/mL