Human Hyaluronan Synthase 2, HAS2 ELISA Kit

SKU: E1578Hu

Size:96 Tests-1 Kit

Background:Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the extracellular matrix (By similarity).

Research_area:Cardiovascular

Applications:ELISA

Target_protein:HAS2

Reactivity:Human

Assay type:Sandwich

Sensitivity:2.69ng/L

Detection range:5-1000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Hyaluronan Synthase 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q92819

MASS(Da):63,566

GeneID:3037

Synonyms:HA Synthase 2;HAS 2;HAS2;Hyaluronan Synthase 2;Hyaluronate Synthase 2;Hyaluronic acid Synthase 2

Gene names:HAS2

Standard solution:1280ng/L