Human Homeobox Protein Hox-D8, HOXD8 ELISA Kit

SKU: E5431Hu

Size:96 Tests-1 Kit

Background:Homeobox protein Hox-D8 is a protein that in humans is encoded by the HOXD8 gene. This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function.

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:HOXD8

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.88ng/L

Detection range:20-3800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Homeobox protein Hox-D8

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P13378

MASS(Da):31,911

GeneID:3234

Synonyms:Homeobox protein Hox-4E;Homeobox protein Hox-5.4;Homeobox protein Hox-D8;HOX4;HOX4E;HOX5.4;HOXD8

Gene names:HOXD8

Standard solution:4000ng/L