Human Histone-lysine N-methyltransferase 2B,KMT2B ELISA KIT

SKU: E7574Hu

Size:96 Tests-1 Kit

Background:Histone methyltransferase that methylates 'Lys-4' of histone H3 (PubMed:17707229). H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation (PubMed:17707229). Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2 (PubMed:17707229). Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development (By similarity). Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation (By similarity). {ECO:0000250|UniProtKB:O08550, ECO:0000269|PubMed:17707229}.

Research_area:

Applications:ELISA

Target_protein:KMT2B

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.19ng/ml

Detection range:0.38-24ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9UMN6

MASS(Da):293515

GeneID:9757

Synonyms:KMT2B HRX2 KIAA0304 MLL2 MLL4 TRX2 WBP7

Gene names:KMT2B

Standard solution:48ng/ml