Human Heat shock protein beta-11,HSPB11 ELISA KIT

SKU: E5377Hu

Size:96 Tests-1 Kit

Background:Component of the IFT complex B required for sonic hedgehog/SHH signaling. May mediate transport of SHH components: required for the export of SMO and PTCH1 receptors out of the cilium and the accumulation of GLI2 at the ciliary tip in response to activation of the SHH pathway, suggesting it is involved in the dynamic transport of SHH signaling molecules within the cilium. Not required for ciliary assembly. Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis. Essential for male fertility, spermiogenesis and sperm flagella formation. Plays a role in the early development of the kidney. May be involved in the regulation of ureteric bud initiation (By similarity). {ECO:0000250|UniProtKB:Q9D6H2}.

Research_area:

Applications:ELISA

Target_protein:HSPB11

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.026ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Heat shock protein beta-11

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9Y547

MASS(Da):16297

GeneID:51668

Synonyms:HSPB11 C1orf41 IFT25 HSPC034

Gene names:HSPB11

Standard solution:24ng/ml