Human Heat Shock Protein 90kDa Beta 1,HSP90b1 ELISA KIT

SKU: E3012Hu

Size:96 Tests-1 Kit

Background:Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD) (PubMed:18264092). Has ATPase activity (By similarity). May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10 (PubMed:32272059). {ECO:0000250|UniProtKB:P08113, ECO:0000269|PubMed:18264092, ECO:0000269|PubMed:32272059}.

Research_area:

Applications:ELISA

Target_protein:HSP90B1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.09ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Heat Shock Protein 90kDa Beta 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P14625

MASS(Da):92469

GeneID:7184

Synonyms:HSP90B1 GRP94 TRA1

Gene names:HSP90B1

Standard solution:24ng/ml