Human Heat Shock Protein 75 kDa, Mitochondrial, HSP75 ELISA Kit

SKU: E5375Hu

Size:96 Tests-1 Kit

Background:Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Research_area:Others

Applications:ELISA

Target_protein:TRAP1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.14ng/mL

Detection range:0.3-90ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Heat shock protein 75 kDa, mitochondrial

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q12931

MASS(Da):80,110

GeneID:10131

Synonyms:Heat shock protein 75 kDa, mitochondrial;HSP 75;HSP75;HSP90L;TNFR-associated protein 1;TRAP1;TRAP-1;Tumor necrosis factor type 1 receptor-associated protein

Gene names:TRAP1

Standard solution:96ng/mL