Human Gamma-aminobutyric acid receptor-associated protein-like 1,GABARAPL1 ELISA KIT

SKU: E7386Hu

Size:96 Tests-1 Kit

Background:Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor (PubMed:16431922). Involved in formation of autophagosomal vacuoles (PubMed:20404487). While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20404487). Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover (PubMed:31006538, PubMed:31006537). {ECO:0000269|PubMed:16431922, ECO:0000269|PubMed:20404487, ECO:0000269|PubMed:31006537, ECO:0000269|PubMed:31006538}.

Research_area:

Applications:ELISA

Target_protein:GABARAPL1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.012ng/ml

Detection range:0.05-15ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Gamma-aminobutyric acid receptor-associated protein-like 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9H0R8

MASS(Da):14044

GeneID:23710

Synonyms:GABARAPL1 GEC1

Gene names:GABARAPL1

Standard solution:16ng/ml