Human Fibroblast Growth Factor 2, FGF2 ELISA Kit

SKU: E0055Hu

Size:96 Tests-1 Kit

Background:Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (PubMed: 8663044). Also acts as an integrin ligand which is required for FGF2 signaling (PubMed: 28302677). Binds to integrin ITGAV:ITGB3 (PubMed: 28302677). Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (PubMed: 8663044, PubMed: 28302677). Functions as a potent mitogen in vitro (PubMed: 1721615, PubMed: 3964259, PubMed: 3732516). Can induce angiogenesis (PubMed: 23469107, PubMed: 28302677). Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (PubMed: 29501879).

Research_area:Cardiovascular; Signal Transduction; Neuroscience; Cancer

Applications:ELISA

Target_protein:FGF2

Reactivity:Human

Assay type:Sandwich

Sensitivity:2.49ng/L

Detection range:5-1500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Fibroblast Growth Factor 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P09038

MASS(Da):30,770

GeneID:2247

Synonyms:Basic fibroblast growth factor;bFGF;FGF 2;FGF2;FGF-2;Fibroblast growth factor 2;HBGF-2;Heparin-binding growth factor 2

Gene names:FGF2

Standard solution:1600ng/L