Human Fad-linked Sulfhydryloxidase Alr, GFER ELISA Kit

SKU: E4735Hu

Size:96 Tests-1 Kit

Background:[Isoform 1]: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. [Isoform 2]: May act as an autocrine hepatotrophic growth factor promoting liver regeneration.

Research_area:Signal Transduction; Cell Biology

Applications:ELISA

Target_protein:GFER

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.54ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Fad-Linked Sulfhydryl Oxidase ALR

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P55789

MASS(Da):23,449

GeneID:2671

Synonyms:Augmenter of liver regeneration;FAD-linked sulfhydryl oxidase ALR;GFER;Hepatopoietin;hERV1

Gene names:GFER

Standard solution:2400ng/L