Human Ephrin Type-B Receptor 4, EPHB4 ELISA Kit

SKU: E5251Hu

Size:96 Tests-1 Kit

Background:Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

Research_area:Cardiovascular

Applications:ELISA

Target_protein:EPHB4

Reactivity:Human

Assay type:Sandwich

Sensitivity:3.17ng/L

Detection range:7-1500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Ephrin type-B receptor 4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P54760

MASS(Da):108,270

GeneID:2050

Synonyms:CMAVM2;EPHB4;Ephrin type-B receptor 4;Hepatoma transmembrane kinase;HFASD;HTK;LMPHM7;MYK1;TYRO11;Tyrosine-protein kinase TYRO11

Gene names:EPHB4

Standard solution:1600ng/L