Human DSG3 ELISA Kit PicoKine®

SKU: EK2190

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: DSG3

Specificity: Natural and recombinant Human DSG3

Background: Desmoglein-3 is a protein that in humans is encoded by the DSG3 gene. This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.

Immunogen: Expression system for standard: NS0; Immunogen sequence: E50-R615

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Reconstitution:

Reference:

Uniprot ID: P32926

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 1830

Protein Name: Desmoglein-3

Gene Full Name: desmoglein 3

Synonyms: Desmoglein-3; CDHF6; DSG3; PVA; Cadherin family member 6; 130 kDa pemphigus vulgaris antigen