Human DNA Topoisomerase 2-alpha, TOP2A ELISA Kit

SKU: E6652Hu

Size:96 Tests-1 Kit

Background:Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand (PubMed:17567603, PubMed:18790802, PubMed:22013166, PubMed:22323612). May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).

Research_area:Epigenetics and Nuclear Signaling; Cancer

Applications:ELISA

Target_protein:TOP2A

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.78ng/L

Detection range:20-3800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:DNA topoisomerase 2-alpha

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P11388

MASS(Da):174,385

GeneID:7153

Synonyms:DNA topoisomerase 2-alpha;DNA topoisomerase II, alpha isozyme;TOP2;TOP2A;TOP2alpha;TOPIIA;TP2A

Gene names:TOP2A

Standard solution:4000ng/L