Human DNA Replication Factor Cdt1, CDT1 ELISA Kit

SKU: E5191Hu

Size:96 Tests-1 Kit

Background:Required for both DNA replication and mitosis (PubMed: 11125146, PubMed: 22581055, PubMed: 21856198, PubMed: 14993212, PubMed: 26842564). DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC)(PubMed: 14672932). Required also for mitosis by promoting stable kinetochore-microtubule attachments (PubMed: 22581055). Potential oncogene (By similarity).

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:CDT1

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.63ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Dna Replication Factor Cdt1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9H211

MASS(Da):60,390

GeneID:81620

Synonyms:CDT 1;CDT1;DNA replication factor Cdt1;Double parked homolog;DUP

Gene names:CDT1

Standard solution:3200ng/L