Human Dickkopf-related Protein 4, DKK4 ELISA Kit

SKU: E5183Hu

Size:96 Tests-1 Kit

Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

Research_area:Stem Cells

Applications:ELISA

Target_protein:DKK4

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.17ng/mL

Detection range:0.3-90ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Dickkopf-Related Protein 4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9UBT3

MASS(Da):24,876

GeneID:27121

Synonyms:Dickkopf-4;Dickkopf-related protein 4;Dickkopf-related protein 4 short form;DKK 4;DKK4;Dkk-4;hDkk-4

Gene names:DKK4

Standard solution:96ng/mL