Human D-amino Acidoxidase Activator, DAOA ELISA Kit

SKU: E2954Hu

Size:96 Tests-1 Kit

Background:D-amino acid oxidase activator (DAOA, also known as G72) is a protein enriched in various parts of brain, spinal cord, and testis. DAOA is thought to interact with D-amino acid oxidase, a peroxisomal enzyme, and its gene was associated with schizophrenia in a number of studies. In separate studies it has been shown to confer susceptibility to bipolar disorder. Therefore, it has been important in researching whether the Kraepelinian dichotomy is genuine. The gene itself was discovered during an investigation of chromosomal 13q22-q34 region, which was previously linked to schizophrenia. G72 is transcribed into several proteins due to alternative splicing; the longest protein is called LG72 and consists of 153 amino acids. Although the protein was initially found to interact with DAO in yeast 2-hybrid experiment, one recent in vivo experiment showed LG72 presence only in mitochondria and failed to confirm the interaction.

Research_area:Others

Applications:ELISA

Target_protein:DAOA

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.051ng/ml

Detection range:0.1-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:D-amino Acid Oxidase Activator

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P59103

MASS(Da):18,108

GeneID:267012

Synonyms:D-amino acid oxidase activator;DAOA;LG72;Protein G72;SG72

Gene names:DAOA

Standard solution:32ng/ml